Hair Loss Hormones- When Genetics
And Body Chemistry Combine To Cause Hair Loss
The scientific term for hair loss is
"alopecia." When caused by hair loss hormones, the term becomes
"androgenic alopecia." There are many causes for hair loss, including
heredity factors, aging, illness and infectious diseases, nervous
disorders, toxic substances, injury, and severe radiation. But hair loss
hormones, combined with genetic factors, are responsible for the most
common types of baldness. What begins as a few lost hairs after shampooing
progresses to a receding hairline and thinning hair. When hair loss occurs
in a specific pattern on the head, it is called "male pattern baldness."
Male pattern baldness is genetic in
cause, due to an autosomal dominant gene. Starting at the temples, male
pattern baldness will progress until there is only a U-shaped fringe of
hair around the head. Some men may have only a receding hairline and/or
baldness at the top (crown) of the head. Hair loss hormones are the
culprits here, assisted by heredity.
Hair loss is an inherited trait. If a man
has the genetic code for hair loss, the follicles on the top his head are
sensitive to the hormone dihydrotestosterone (DHT), making them
predisposed to shrinkage and to the actions of hair loss hormones. DHT is
a potent and active form of testosterone that is produced by the action of
the enzyme 5-alpha-reductase. This enzyme is produced in the prostate,
adrenals and the scalp and actually converts the testosterone to DHT.
When DHT attacks a follicle, it sets up a reaction by the immune system
that causes the body to react to the follicle as a foreign body. Here's
how:
Everybody naturally loses a few hairs a
day, from combing, brushing or shampooing. When a hair is shed, it leaves
the follicle open and unprotected. If DHT is present in the sebum (oil) of
the scalp, it will migrate into the empty follicle. What happens then is
that this strongest of the hair loss hormones shrinks the hair root and
follicle. The next hair that grows will be thin and subsequent hairs will
be thinner and thinner. Eventually the follicle stops producing hair. This
process will occur over a larger and larger area of the scalp, at first as
thinning and patchiness
and later as baldness. About 40 million men in the U.S. are affected --
25% of these will begin losing significant amounts of hair, due to hair
loss hormones, by age 30.
Researchers and doctors have reasoned
that if DHT and other hair loss hormones interrupt the normal
physiological environment and function of hair follicles, then blocking
the action of DHT might have the effect of slowing hair loss. To date, the
FDA has approved only 2 such treatments, RogaineŽ and PropeciaŽ. There are
a variety of other treatments available, including many cost-effective
natural and herbal remedies that also block DHT. When seeking a solution
to thinning hair or baldness, remember that genetic factors and hair loss
hormones are the most common causes. It's important to determine the
correct cause. If DHT is a factor in your hair loss, there are effective
treatments to slow or stop it.
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